Direct somatic lineage conversion
نویسندگان
چکیده
منابع مشابه
Direct somatic lineage conversion.
The predominant view of embryonic development and cell differentiation has been that rigid and even irreversible epigenetic marks are laid down along the path of cell specialization ensuring the proper silencing of unrelated lineage programmes. This model made the prediction that specialized cell types are stable and cannot be redirected into other lineages. Accordingly, early attempts to chang...
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ژورنال
عنوان ژورنال: Philosophical Transactions of the Royal Society B: Biological Sciences
سال: 2015
ISSN: 0962-8436,1471-2970
DOI: 10.1098/rstb.2014.0368